Design and analysis of PZT micropumps for biomedical applications: Glaucoma treatment
Özet
Micropumps have wide range of novel applications in medical field. The main purpose of this study was to find potential electro-mechanical design aspects of a micropump for Glaucoma disease treatment. We suggested four new micropump designs, namely, single diaphragm micropumps at two different Piezoelectric Lead Zirconate Titanate (PZT-2) thicknesses, a bi-diaphragm micropump, and a peristaltic micropump. The driving voltage values in the simulations were 5 V to 45 V by 5 V increments and the frequencies were 5 Hz and 10 Hz. Two dimensional analyses were done with COMSOL Multiphysics 4.3. Three different one-way Analysis of Variance (ANOVA) analyses were performed to find out the effect of voltage and frequencies on flow rates. At different frequencies, there were significant differences in flow rates and fluid pressures (p < 0.05) for each micropump design. At different driving voltages, flow rates, displacement values, and fluid pressures were statistically different (p < 0.001) for all micropumps. The maximum flow rate obtained in peristaltic micropump was 1.62 x 10(-27) m(3)/cycle. The maximum displacement of diaphragm occurred in bi-diaphragm micropump was 3.68 x 10(-3) mm, which was obtained at 45 V and 5 Hz. According to our result, peristaltic micropump design might be used for glaucoma treatment.