Yazar "Yakan, Hasan" için listeleme
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1,2,3-Triazole substituted phthalocyanine metal complexes as potential inhibitors for anticholinesterase and antidiabetic enzymes with molecular docking studies
Koçyiğit, Ümit M.; Taslimi, Parham; Tüzün, Burak; Yakan, Hasan; Muglu, Halit; Güzel, Emre (Taylor & Francis Inc, 2020)In recent years, acetylcholinesterase (AChE) and alpha-glycosidase (alpha-gly) inhibition have emerged as a promising and important approach for pharmacological intervention in many diseases such as glaucoma, epilepsy, ... -
Determination of biological studies and molecular docking calculations of isatin-thiosemicarbazone hybrid compounds
Kocyigit, Umit M.; Dogan, Murat; Muglu, Halit; Taslimi, Parham; Tuzun, Burak; Yakan, Hasan; Bal, Halil (Elsevier, 2022)Design, synthesis, structural elucidation, and investigation of cytotoxic and antimicrobial activity, butyrylcholinesterase (BChE), and acetylcholinesterase (AChE) enzyme inhibition effects of isatinthiosemicarbazone hybrid ... -
Exploring of antioxidant and antibacterial properties of novel 1,3,4-thiadiazole derivatives: Facile synthesis, structural elucidation and DFT approach to antioxidant characteristics
Muglu, Halit; Akin, Mustafa; Cavus, M. Serdar; Yakan, Hasan; Saki, Neslihan; Guzel, Emre (Elsevier Sci Ltd, 2022)In recent years, compounds containing thiophene and 1,3,4-thiadiazole skeletons have become important cyclic compounds, especially in medicinal chemistry. In this manner, we synthesized and isolated seven 1,3,4-thiadiazole ... -
New Schiff bases based on isatin and (thio)/carbohydrazone: preparation, experimental-theoretical spectroscopic characterization, and DFT approach to antioxidant characteristics
Muglu, Halit; Sonmez, Fatih; Cavus, M. Serdar; Kurt, Belma Z.; Yakan, Hasan (Springer, 2022)In this study, synthesis, spectroscopic elucidation, and investigation of antioxidant properties of new Schiff bases based on isatin and (thio)/carbohydrazone derivatives have been reported for the first time. The structures ... -
New Schiff bases based on isatin and (thio)/carbohydrazone: preparation, experimental–theoretical spectroscopic characterization, and DFT approach to antioxidant characteristics
Muğlu, Halit; Sönmez, Fatih; Çavuş, M. Serda; Kurt, Belma Z.; Yakan, Hasan (Springer Science and Business Media B.V., 2023)In this study, synthesis, spectroscopic elucidation, and investigation of antioxidant properties of new Schiff bases based on isatin and (thio)/carbohydrazone derivatives have been reported for the first time. The structures ... -
New Schiff bases based on isatin and (thio)/carbohydrazone: preparation, experimental–theoretical spectroscopic characterization, and DFT approach to antioxidant characteristics
Muğlu, Halit; Sönmez, Fatih; Çavuş, M. Serdar; Kurt, Belma Z.; Yakan, Hasan (Springer Science and Business Media B.V., 2023)In this study, synthesis, spectroscopic elucidation, and investigation of antioxidant properties of new Schiff bases based on isatin and (thio)/carbohydrazone derivatives have been reported for the first time. The structures ... -
A new series of asymmetric bis-isatin derivatives containing urea/thiourea moiety: Preparation, spectroscopic elucidation, antioxidant properties and theoretical calculations
Yakan, Hasan; Cavuş, M. Serdar; Zengin Kurt, Belma; Muglu, Halit; Sönmez, Fatih; Güzel, Emre (Elsevier, 2021)In the present study, design, synthesis, characterization, and investigation of antioxidant properties of novel asymmetric bis-isatin derivatives (1-8) containing urea/thiourea moiety are reported for the first time. FT-IR, ... -
Potential thiosemicarbazone-based enzyme inhibitors: Assessment of antiproliferative activity, metabolic enzyme inhibition properties, and molecular docking calculations
Yakan, Hasan; Kocyigit, Umit M.; Muglu, Halit; Ergul, Mustafa; Erkan, Sultan; Guzel, Emre; Taslimi, Parham (Wiley, 2022)A new series of thiosemicarbazone derivatives (1-11) were prepared from various aldehydes and isocyanates with high yields and practical methods. The structures of these compounds were elucidated by Fourier transform ... -
Preparation, antioxidant activity, and theoretical studies on the relationship between antioxidant and electronic properties of bis(thio/carbohydrazone) derivatives
Muglu, Halit; Kurt, Belma Zengin; Sonmez, Fatih; Guzel, Emre; Cavul, M. Serdar; Yakan, Hasan (Pergamon-Elsevier Science Ltd, 2022)A series of novel bis(thio/carbohydrazone) compounds has been prepared from (thio)/carbohydrazide and various aldehyde derivatives. FTIR, H-1 and C-13 NMR spectroscopy, and elemental analysis have been used to elucidate ...