Yazar "Okuyan, Hamza Malik" için listeleme
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Association of miR-21-5p with routine biochemical markers and inflammatory cytokines in hemodialysis patients
Okuyan, Hamza Malik; Terzi, Menderes Yusuf; Dogan, Serdar; Emir, Türkan; Turgut, Faruk Hilmi (Elsevier Inc., 2023)Background: Although the role of miR-21-5p in some kidney diseases is relatively documented, the relationship of miR-21-5p with markers of bone metabolism and inflammation in patients receiving hemodialysis (HD) remains ... -
Association of serum lncRNA H19 expression with inflammatory and oxidative stress markers and routine biochemical parameters in chronic kidney disease
Okuyan, Hamza Malik; Doğan, Serdar; Terzi, Menderes Yusuf; Beğen, Mehmet A.; Turgut, Faruk Hilmi (Springer, 2021)Background Chronic kidney disease (CKD) is a disorder that affects millions worldwide, and current treatment options aiming at inhibiting the progression of kidney damage are limited. Long noncoding RNA (lncRNA) H19 is one ... -
Beclin-1, an autophagy-related protein, is associated with the disease severity of COVID-19
Okuyan, Hamza Malik; Doğan, Serdar; Bal, Tayibe; Cabalak, Mehmet (Pergamon-Elsevier Science Ltd, 2021)Aims: Coronavirus disease 2019 (COVID-19), which is a highly contagious disease, is an ongoing outbreak worldwide with high morbidity and mortality. The approaches targeting the autophagy processes might have promising ... -
Comparison of the protective effect of the upper zone of the growth plate and unique cartilage matrix-associated protein with hyaluronic acid and corticosteroids on an experimental rat osteoarthritis model
Gökdemir, Cemil Emre; Okuyan, Hamza Malik; Karaboğa, İhsan; Terzi, Menderes Yusuf; Kalacı, Aydıner (Turkish League Against Rheumatism (TLAR), 2024)Objectives: This study sought to compare the protective effect of the upper zone of the growth plate and unique cartilage matrix-associated protein (UCMA) with hyaluronic acid (HA) and corticosteroids (CS) in a rat model ... -
Correction: Urotensin-II Prevents Cartilage Degeneration in a Monosodium Iodoacetate-Induced Rat Model of Osteoarthritis (International Journal of Peptide Research and Therapeutics, (2022), 28, 5, (140), 10.1007/s10989-022-10448-4)
Terzi, Menderes Yusuf; Okuyan, Hamza Malik; Karaboğa, İhsan; Gökdemir, Cemil Emre; Tap, Duygu; Kalacı, Aydıner (Springer Science and Business Media B.V., 2024)The original version of this article unfortunately contained error in Fig. 2 as the images of Panels MIA + UII-2, femoral and tibial are incorrect. The corrected Fig. 2 is presented here. (Figure presented.) Gross morphology ... -
Ebselen, an Active Seleno-Organic Compound, Alleviates Articular Cartilage Degeneration in a Rat Model of Knee Osteoarthritis
Okuyan, Hamza Malik; Yurtal, Ziya; Karaboga, Ihsan; Kacmaz, Filiz; Kalaci, Aydiner (Springernature, 2022)Osteoarthritis (OA) is a prevalent articular disease mainly characterized by extracellular matrix degradation, apoptosis, and inflammation, which lead to cartilage destruction and abnormal bone metabolism. With undesirable ... -
Expression level of UCMA as a candidate molecular target in osteoarthritis
Okuyan, Hamza Malik; Arslan, Ahmet; Iğcı, Yusuf Ziya; Göğebakar, Bülent; Bilgiç, Nilüfer; Gündüz, Kübra; Sönmez, Dilara (2021)Aim: Osteoarthritis (OA) is a degenerative joint disorder that damages cartilage, synovium and subchondral bone, and there is yet no effective treatment for OA. The identification of novel therapeutic methods is crucially ... -
In vivo protective effects of upper zone of growth plate and cartilage matrix associated protein against cartilage degeneration in a monosodium iodoacetate induced osteoarthritis model
Okuyan, Hamza Malik; Terzi, Menderes Yusuf; Karaboga, İhsan; Doğan, Serdar; Kalacı, Aydıner (Canadian Science Publishing, 2020)Osteoarthritis (OA) is a degenerative disease affecting the majority of over 65 year old people and characterized by cartilage degeneration, subchondral abnormal changes, and inflammation. Despite the enormous socioeconomic ... -
LncRNAs in Osteoarthritis
Okuyan, Hamza Malik; Begen, Mehmet A. (Elsevier, 2022)Osteoarthritis (OA) is a progressive joint disease that affects millions of older adults around the world. With increasing rates of incidence and prevalence worldwide, OA has become an enormous global socioeconomic burden ... -
miRNAs as attractive diagnostic and therapeutic targets for Familial Mediterranean Fever
Okuyan, Hamza Malik; Beğen, Mehmet A. (Taylor & Francis Ltd, 2021)Familial Mediterranean Fever (FMF) is a hereditary early-onset disease that causes periodical fever attack, excessive release of IL-1 beta, serositis, arthritis and peritonitis. Genetic analyses conducted on FMF patients ... -
Prenatal immobility stress: Relationship with oxidative stress, inflammation, apoptosis, and intrauterine growth restriction in rats
Kaya, Sinem Albayrak; Okuyan, Hamza Malik; Erboğa, Zeynep Fidanol; Güzel, Savaş; Yılmaz, Ahsen; Karaboğa, İhsan (John Wiley and Sons Inc, 2023)Background: Prenatal stress is a significant risk factor affecting pregnant women and fetal health. In the present study, we aimed to investigate the effect of immobility stress at different periods of pregnancy on oxidative ... -
Relationship of thrombospondin-1 and thrombospondin-2 with hematological, biochemical and inflammatory markers in covid-19 patients
Dogan, Serdar; Okuyan, Hamza Malik; Bal, Tayibe; Çabalak, Mehmet; Begen, Mehmet A. (De Gruyter Open Ltd, 2023)Objectives: Roles of thrombospondin-1 (TSP-1) and thrombospondin-2 (TSP-2) in tissue repair and inflammation are well-documented, but the association of their serum expressions with the pathogenesis of COVID-19 remains ... -
Upper Zone of Growth Plate and Cartilage Matrix (UCMA) Levels in Patients with Chronic Kidney Disease
Okuyan, Hamza Malik; Özcan, Oğuzhan; Doğan, Serdar; Arpacı, Abdullah; Turgut, Faruk Hilmi (Inst Tecnologia Parana, 2020)Chronic kidney disease (CKD) is an important health problem across the world affecting the adult population with an enormous social and economic burden. Calcium regulation is also affected in patients with CKD, and related ... -
Urotensin-II Prevents Cartilage Degeneration in a Monosodium Iodoacetate-Induced Rat Model of Osteoarthritis
Terzi, Menderes Yusuf; Okuyan, Hamza Malik; Karaboga, Ihsan; Gokdemir, Cemil Emre; Tap, Duygu; Kalaci, Aydiner (Springer, 2022)Osteoarthritis (OA) is a common degenerative articular disorder caused by traumatic or spontaneous factors such as genetics, obesity, and advanced age. Comprehending the pathogenic mechanism of OA ensures the development ... -
UROTENSİN II’NİN İNSAN OSTEOBLAST HÜCRELERİNDE ENFLAMASYONLA İLİŞKİLİ ROLÜ
Osteoartrit (OA), kemik, kıkırdak ve sinoviyal dokuda katabolik değişikliklere neden olan yaygın bir eklem hastalığıdır. OA’nıngüncel tedavisi, hastalığı tamamen iyileştirmek için yeterli değildir. Eklem kondrositlerinin ...