Yazar "Doğan, Berna" için listeleme
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Synthesis, biological activity and multiscale molecular modeling studies of bis-coumarins as selective carbonic anhydrase IX and XII inhibitors with effective cytotoxicity against hepatocellular carcinoma
Kurt, Belma Zengin; Dağ, Aydan; Doğan, Berna; Durdağı, Serdar; Angeli, Andrea; Nocentini, Alessio; Sönmez, Fatih (Academic Press Inc Elsevier Science, 2019)A series of novel bis-coumarin derivatives containing triazole moiety as a linker between the alkyl chains was synthesized and their inhibitory activity against the human carbonic anhydrase (hCA) isoforms I, II, IX and XII ... -
Synthesis, molecular docking and molecular dynamics studies of novel tacrine-carbamate derivatives as potent cholinesterase inhibitors
Özten, Özge; Kurt, Belma Zengin; Sönmez, Fatih; Doğan, Berna; Durdağı, Serdar (Academic Press Inc Elsevier Science, 2021)In the present study, new tacrine derivatives containing carbamate group were synthesized and their acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition activities were evaluated. All synthesized compounds ...