Yazar "Angeli, Andrea" için listeleme
-
Quinoline-sulfamoyl carbamates/sulfamide derivatives: Synthesis, cytotoxicity, carbonic anhydrase activity, and molecular modelling studies
Çakmak, Elmas Begüm; Kurt, Belma Zengin; Civelek, Dilek Özturk; Angeli, Andrea; Akdemir, Atilla; Sönmez, Fatih; Kücükislamoğlu, Mustafa (Academic Press Inc Elsevier Science, 2021)Carbonic anhydrase (CA) IX, and XII isoforms are known to be highly expressed in various human tissues and malignancies. CA IX is a prominent target for some cancers because it is overexpressed in hypoxic tumors and this ... -
Synthesis of coumarin-sulfonamide derivatives and determination of their cytotoxicity, carbonic anhydrase inhibitory and molecular docking studies
Kurt, Belma Zengin; Sönmez, Fatih; Öztürk, Dilek; Akdemir, Atilla; Angeli, Andrea; Supuran, Claudiu T. (Elsevier France-Editions Scientifiques Medicales Elsevier, 2019)Carbonic anhydrases isoforms CA IX, and XII are known to be highly expressed in various human tissues and malignancies. CA IX is a prominent target for especially colorectal cancers, because it is overexpressed in colorectal ... -
Synthesis, biological activity and multiscale molecular modeling studies of bis-coumarins as selective carbonic anhydrase IX and XII inhibitors with effective cytotoxicity against hepatocellular carcinoma
Kurt, Belma Zengin; Dağ, Aydan; Doğan, Berna; Durdağı, Serdar; Angeli, Andrea; Nocentini, Alessio; Sönmez, Fatih (Academic Press Inc Elsevier Science, 2019)A series of novel bis-coumarin derivatives containing triazole moiety as a linker between the alkyl chains was synthesized and their inhibitory activity against the human carbonic anhydrase (hCA) isoforms I, II, IX and XII ...