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Synthesis of coumarin-sulfonamide derivatives and determination of their cytotoxicity, carbonic anhydrase inhibitory and molecular docking studies
Kurt, Belma Zengin; Sönmez, Fatih; Öztürk, Dilek; Akdemir, Atilla; Angeli, Andrea; Supuran, Claudiu T. (Elsevier France-Editions Scientifiques Medicales Elsevier, 2019)Carbonic anhydrases isoforms CA IX, and XII are known to be highly expressed in various human tissues and malignancies. CA IX is a prominent target for especially colorectal cancers, because it is overexpressed in colorectal ...